연구실적
-
2025.08 |
교신저자 |
BMB REPORTS,
제58권
8호
, pp.364-368
Kinetic basis for Cas12a off-target discrimination -
2025.01 |
교신저자 |
BIOSENSORS & BIOELECTRONICS,
제267권
1호
, pp.116859-116859
Enhanced trans-cleavage activity using CRISPR-Cas12a variant designed to reduce steric inhibition by cis-cleavage products -
2024.12 |
교신저자 |
MOLECULES AND CELLS,
제47권
12호
, pp.100150-100150
Single-molecule FRET-based approach for protein-targeted drug discovery -
2024.11 |
교신저자 |
CHEMICAL COMMUNICATIONS,
제60권
89호
, pp.13087-13090
Effects of steric hindrance from single-stranded overhangs on target-strand loading into the Cas12a active site -
2024.01 |
공동저자 |
JOURNAL OF CONTROLLED RELEASE,
제365권
0호
, pp.703-715
A radioactive CRISPR interference system using 89Zr-labeled LbCas12a -
2023.03 |
교신저자 |
BIODESIGN,
제11권
1호
, pp.11-15
Single-molecule fluorescence assays for studying the mechanism of DNA cleavage by CRISPR-Cas12a
- 2024.11 | KAGE-GERP 2024 공동학술대회 | 국내학술대회(포스터)
Development of CRISPR-Cas12a variant designed to improve the performance of Cas12a by exploiting the molecular mechanism - 2024.10 | 2024 KPS Fall Meeting | 국내학술대회(포스터)
Molecular mechanisms underlying the enhanced activity of Cas12a-induced trans-cleavage under low ionic strength conditions - 2024.10 | 2024 KPS Fall Meeting | 국내학술대회(포스터)
Effect of mismatches in DNA flap structure on flap dynamics and resulting FEN1 activity - 2024.10 | 2024 KPS Fall Meeting | 국내학술대회(포스터)
Single-molecule dissection of DNA cleavage by CRISPR-Cas12a: A comparative study of AsCas12a and LbCas12a - 2023.11 | 제18회 한국유전자세포치료학회 정기학술대회 | 국내학술대회(구연)
Constructing next-generation type V CRISPR-Cas tools from structural dynamics - 2023.10 | 2023 KPS Fall Meeting | 국내학술대회(포스터)
Prism-based spectral analysis for single-molecule FRET measurement - 2023.01 | 제3회 생물물리분과 학술대회 | 국내학술대회(포스터)
Mg2+-induced conformational changes of Cas12a ternary complex are necessary for complete double-strand breaks in the target DNA