가톨릭대학교 THE CATHOLIC UNIVERSITY OF KOREA가톨릭대학교 THE CATHOLIC UNIVERSITY OF KOREA의과대학

가톨릭대학교 THE CATHOLIC UNIVERSITY OF KOREA가톨릭대학교 THE CATHOLIC UNIVERSITY OF KOREA의과대학

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기초의학교실


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조영애 교수

Young-Ae Joe

연구실적

  • 2025.07 | 교신저자 | BIOMOLECULES & THERAPEUTICS, 제33권 4호 , pp.606-620
    Identification of Autophagy-Related Prognostic Signature for Glioblastoma Standard Therapy
  • 2024.11 | 교신저자 | BIOMOLECULES & THERAPEUTICS, 제32권 6호 , pp.685-696
    Experimental Mouse Models and Human Lung Organoid Models for Studying Chronic Obstructive Pulmonary Disease
  • 2023.01 | 교신저자 | BIOMOLECULES & THERAPEUTICS (응용약물학회지,THE JOURNAL OF APPLIED PHARMACOLOGY), 제31권 1호 , pp.1-15
    Enhancing Anti-Cancer Therapy with Selective Autophagy Inhibitors by Targeting Protective Autophagy
  • 2023.01 | 교신저자 | 생명과학회지, 제33권 1호 , pp.8-14
    Peroxidase Activity of Peroxidasin Affects Endothelial Cell Growth
  • 2022.11 | 교신저자 | BIOMOLECULES & THERAPEUTICS(응용약물학회지,THE JOURNAL OF APPLIED PHARMACOLOGY), 제30권 6호 , pp.616-624
    Modulation of Autophagy is a Potential Strategy for Enhancing the Anti-Tumor Effect of Mebendazole in Glioblastoma Cells
  • 2020.08 | 교신저자 | FASEB JOURNAL, 제34권 8호 , pp.10228-10241
    Peroxidasin is essential for endothelial cell survival and growth signaling by sulfilimine crosslink-dependent matrix assembly
  • 2019.12 | 교신저자 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 제20권 24호 , pp.6144-6144
    Biallelic Deletion of Pxdn in Mice Leads to Anophthalmia and Severe Eye Malformation
  • 2019.01 | 교신저자 | STEM CELLS, 제37권 1호 , pp.77-88
    A Subset of Paracrine Factors as Efficient Biomarkers for Predicting Vascular Regenerative Efficacy of Mesenchymal Stromal/Stem Cells
  • 2019.01 | 교신저자 | BIOMOLECULES & THERAPEUTICS(응용약물학회지,THE JOURNAL OF APPLIED PHARMACOLOGY), 제27권 1호 , pp.117-125
    Autophagy Is a Potential Target for Enhancing the Anti-Angiogenic Effect of Mebendazole in Endothelial Cells
  • 2018.07 | 교신저자 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 제501권 4호 , pp.941-947
    Autophagy mediates enhancement of proangiogenic activity by hypoxia in mesenchymal stromal/stem cells
  • 2018.02 | 교신저자 | ONCOTARGET, 제9권 11호 , pp.9951-9962
    Urokinase-derived peptide UP-7 suppresses tumor angiogenesis and metastasis through inhibition of FAK activation
  • 2017.05 | 교신저자 | JOURNAL OF CELLULAR BIOCHEMISTRY, 제118권 5호 , pp.1132-1143
    A Novel Peptide Derived From Tissue-Type Plasminogen Activator Potently Inhibits Angiogenesis and Corneal Neovascularization
  • 2015.05 | 교신저자 | CANCER LETTERS, 제360권 2호 , pp.195-204
    The synergistic effect of combination temozolomide and chloroquine treatment is dependent on autophagy formation and p53 status in glioma cells
  • 2015.03 | 공동저자 | INTERNATIONAL JOURNAL OF NANOMEDICINE, 제10권 00호 , pp.2261-2272
    Silica nanoparticles increase human adipose tissue-derived stem cell proliferation through ERK1/2 activation
  • 2015.02 | 교신저자 | JOURNAL OF CELLULAR BIOCHEMISTRY, 제116권 2호 , pp.310-319
    Priming Wharton's Jelly-Derived Mesenchymal Stromal/Stem Cells With ROCK Inhibitor Improves Recovery in an Intracerebral Hemorrhage Model
  • 2013.11 | 교신저자 | BIOMOLECULES & THERAPEUTICS(응용약물학회지,THE JOURNAL OF APPLIED PHARMACOLOGY), 제21권 6호 , pp.447-453
    A ROCK inhibitor blocks the inhibitory effect of chondroitin sulfate proteoglycan on morphological changes of mesenchymal stromal/stem cells into neuron-like cells
  • 2013.03 | 교신저자 | INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 제45권 3호 , pp.560-570
    Proangiogenic features of Wharton's jelly-derived mesenchymal stromal/stem cells and their ability to form functional vessels
  • 2012.03 | 공동저자 | IUBMB LIFE, 제64권 3호 , pp.259-265
    The recombinant kringle domain of urokinase plasminogen activator inhibits VEGF165-induced angiogenesis of HUVECs by suppressing VEGFR2 dimerization and subsequent signal transduction
  • 2012.01 | 교신저자 | BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 제76권 1호 , pp.172-175
    Enhancement of Endothelial Progenitor Cell Numbers and Migration by H1152, a Rho Kinase Specific Inhibitor
  • 2011.09 | 교신저자 | INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 제28권 3호 , pp.357-363
    The Rho kinase inhibitor fasudil augments the number of functional endothelial progenitor cells in ex vivo cultures
  • 2011.03 | 공동저자 | EXPERIMENTAL AND THERAPEUTIC MEDICINE, 제2권 2호 , pp.343-348
    Metronomic treatment of temozolomide increases anti-angiogenicity accompanied by down-regulated O6-methylguanine-DNA methyltransferase expression in endothelial cells
  • 2011.01 | 공동저자 | ONCOLOGY LETTERS, 제2권 1호 , pp.115-121
    Inhibition of STAT3 reverses drug resistance acquired in temozolomide-resistant human glioma cells
  • 2011.01 | 교신저자 | FASEB JOURNAL, 제25권 1호 , pp.159-169
    Efficient nonadhesive ex vivo expansion of early endothelial progenitor cells derived from CD34(+) human cord blood fraction for effective therapeutic vascularization
  • 2006.04 | 공동
    최신의과학용어사전
  • 2003.03 | 공동
    생물정보학-유전자와 단백질 분석에 관한 실용지침서
  • 2913.07 | The 11th Japan-Korea Joint Symposium on Vascular Biology | 국제학술대회(포스터)
    ECM motifs and peroxidase activity are essential for peroxidasin function in endothelial cells
  • 2024.07 | 제 12회 DDC 신약개발컨소시엄 제주 워크샵 | 국내학술대회(구연)
    Roe of peroxidase peroxidasin in lung development and function
  • 2023.10 | The 31st Annual Meeting and Symposium of the Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    Role of peroxidasin in vascular smooth muscle cells and its implication in varicose vein
  • 2023.04 | 2023 Spring Symposium of Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    Identification and validation of autophagy-related prognostic marker for effective temozolomide and radiation therapy of glioblastoma
  • 2022.10 | The 30th Annual Meeting of the Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    Role of matrix peroxidase, peroxidasin in in vitro angiogenesis
  • 2022.10 | The 30th Annual Meeting of the Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    Structural feature and sulfilimine-crosslink activity of peroxidasin mutants required for extracellular matrix assembly
  • 2022.03 | The 6th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies | 국제학술대회(포스터)
    Modulation of autophagy is a potential strategy for enhancing the anti-tumor effect of mebendazole in glioma cell lines
  • 2022.03 | The 6th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies | 국제학술대회(포스터)
    Development of autophagy-related prognostic signature for glioblastoma standard therapy
  • 2021.10 | The 29th Annual meeting of the Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    Autophagy inhibitor enhances the anti-tumor effect of anthelmintic mebendazole in glioma cell lines
  • 2021.10 | The 29th Annual meeting of the Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    Identification of prognostic signature for glioblastoma standard therapy
  • 2021.05 | KSBMB International Conference 2021 | 국제학술대회(구연)
    Role of peroxidasin, a matrix peroxidase, in extracellular matrix assembly and organ development
  • 2020.09 | The 21st International Vascular Biology Meeting | 국제학술대회(포스터)
    Evaluation of the Impact of Peroxidasin On in Vitro and In Vivo Vessel Formation
  • 2020.09 | The 21st International Vascular Biology Meeting | 국제학술대회(포스터)
    The Impact of Oligomerization and Enzymatic Activity of Peroxidasin on Endothelial Cell Function
  • 2020.01 | 제5회 하이원신약개발 심포지아 | 국내학술대회(구연)
    Peroxidasin is essential for eye function
  • 2019.12 | ASCB EMBO 2019 meeting | 국제학술대회(포스터)
    Depletion of Pxdn in Mice Leads to Severely Disorganized Eye Structure in Homozygote in Contrast to Normal Visual Function in Heterozygote
  • 2019.10 | 2019 Annual Meeting of The Korea Society of Applied Pharmacology | 국제학술대회(포스터)
    Deletion of Pxdn in mice leads to anophthalmia and severe eye malformation in homozygote in contrast to normal visual function in heterozygote
  • 2019.10 | 2019 International Conference: Korean Society for Molecular and Cellular Biology | 국제학술대회(포스터)
    Exon 1 deletion of peroxidasin gene in mice leads to drastically disorganized eye structure in homozygote in contrast to normal visual function in heterozygote
  • 2019.07 | 7th KSBMB DDC Jeju Workshop | 국내학술대회(구연)
    Efficient biomarkers for predicting vascular regenerative efficacy of mesenchymal stromal/stem cells
  • 2019.06 | 45th Annual Meeting of Korean Cancer Association & 5th International Cancer Conference | 국제학술대회(포스터)
    Bioinformatics analysis of prognostic autophagy marker for TMZ/radiation treated glioblastoma patients
  • 2019.03 | 2019 Annual Meeting of Korean Society for Neuro-Oncology | 국내학술대회(구연)
    Evaluation of usefulness of autophagic markers for predicting prognosis of TMZ/radiation treated glioblastoma patients
  • 2018.10 | 2018 Annual Meeting of the Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    Mebendazole promotes autophagy and inhibits cellular activity in endothelial cells
  • 2018.10 | 2018 Annual Meeting of the Korean Society for Vascular Biology and Medicine & KVBM-IBS Joint Symposium | 국내학술대회(포스터)
    Autophagy mediates enhancement of proangiogenic activity by hypoxia in mesenchymal stromal/stem cells
  • 2018.07 | 6th KSBMB DDC JeJu Workshop | 국내학술대회(구연)
    Peroxidasin is a putative novel target for angiogenesis inhibition
  • 2018.06 | 2018 IVBM | 국제학술대회(포스터)
    Peroxidasin is essential for endothelial cell behavior and signaling through contributing to extracellular matrix assembly
  • 2018.06 | 2018 24th IUBMB Congress & 15th FAOBMB Congress | 국제학술대회(포스터)
    Autophagy mediates enhancement of proangiogenic activity by hypoxia in mesenchymal stromal/stem cells
  • 2018.06 | 24th IUBMB Congress & 15th FAOBMB Congress | 국제학술대회(포스터)
    Mebendazole inhibits endothelial cell behavior, but not by direct inhibition of growth factor signaling
  • 2017.10 | 2017 Annual Meeting of The Korea Society of Applied Pharmacology | 국제학술대회(포스터)
    Biomarkers for evaluation of proangiogenic therapeutic efficacy of mesenchymal stromal/stem cells
  • 2017.08 | The 15th Japan-Korea Joint Symposium on Vascular Biology, 2017 Annual Meeting of the Korean Vascular Science and Medicine Organization | 국제학술대회(포스터)
    Secretion profile of paracrine factors predicts proangiogenic therapeutic efficacy of mesenchymal stromal /stem cells.
  • 2017.06 | ISSCR 2017 annual meeting | 국제학술대회(포스터)
    Secretion profile of paracrine factors predicts proangiogenic efficacy of mesenchymal stromal/stem cells
  • 2017.04 | AACR 2017 annual meeting | 국제학술대회(포스터)
    Urokinase-derived peptide UP-7 effectively inhibits metastatic growth of breast cancer through suppression of FAK activation
  • 2017.03 | 2017 대한신경종양학회 춘계학술대회 | 국내학술대회(구연)
    Screening of microRNAs associated with non-MGMT related temozolomide resistance in Glioblastoma
  • 2017.01 | 제2회 하이원 신약개발 심포지아 | 국내학술대회(포스터)
    Recombinant peroxidasin promotes cellular survival and growth in serum free culture
  • 2016.10 | 2016 Annual Meeting of the Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    Purified recombinant peroxidasin promotes cellular survival and growth in serum free culture
  • 2016.07 | 24th BIENNIAL CONGRESS OF THE EUROPEAN ASSOCIATION FOR CANCER RESEARCH | 국제학술대회(포스터)
    Urokinase kringle-derived peptide UP7 suppresses tumor angiogenesis and breast cancer metastasis
  • 2016.05 | 2016 KSBMB International Conference | 국제학술대회(포스터)
    Sulfilimine formation in Collagen IV by peroxidasin is essential for enodothelial cell signaling
  • 2016.05 | 2016 KSBMB International Conference | 국제학술대회(포스터)
    Urokinase-derived peptide UP-7 potently suppresses tumor growth and metastasis through suppression of FAK activation
  • 2015.10 | 2015 Annual Meeting of Vascular Science & Medicine Organization, In conjunction with 2015 Asia-Australia Vascular Biology Biennale & 13th Japan-Korea Joint Symposium on Vascular Biology | 국제학술대회(포스터)
    Sulfilimine cross-link by peroxidasin is required for ECM-mediated signaling in endothelial cells
  • 2015.10 | 2015 Annual Meeting of the Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    UP-7 peptide inhibits tumor growth and metastasis of MDA-MB231 breast cancer in xenograft models
  • 2015.07 | KSBMB DDC Summer Workshop | 국내학술대회(구연)
    The synergistic effect of combination treatment of temozolomide and chloroquine treatment is depend on autophagy formation and p53 status in glioblastoma cell line
  • 2015.07 | 2015 응용약물학회 하계 워크샵 | 국내학술대회(구연)
    Peroxidasin forming sulfilimine bonds in collagen IV is a putative novel target for anti-angiogenesis
  • 2015.06 | ISSCR 2015 Annual meeting | 국제학술대회(포스터)
    Direct conversion of cord matrix derived mesenchymal stromal cells to endothelial cells by non-oncogenic transcription factors
  • 2015.05 | 2015 KSBMB International Conference | 국제학술대회(포스터)
    The synergistic effect of combination treatment of temozolomide and chloroquine treatment is depend on autophagy formation and p53 status in glioblastoma cell line
  • 2015.05 | 2015 KSBMB Inernational Conference | 국제학술대회(포스터)
    A novel peptide derived from a β-sheet motif of the kringle 2 domain of tissue-type plasminogen activator effectively inhibits angiogenesis and corneal neovascularization
  • 2014.11 | 2014 Annual Meeting of Vascular Science & Medicine organization | 국내학술대회(포스터)
    Urokinase kringle-derived peptide potently suppresses angiogenesis and tumor metastasis
  • 2014.11 | 2014 Annual Meeting of Vascular Science & Medicine organization | 국내학술대회(포스터)
    Assembly of the extra cellular matrix by peroxidasin is critical for angiogenesis
  • 2014.10 | 2014 Annual Meeting of the Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    Synergistic pro-apoptotic effect from combination treatment with temozolomide and chloroquine is dependent on autophagy formation and p53 status in glioma cells
  • 2014.10 | 2014 Annual Meeting of the Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    TP-7, a novel peptide derived from tissue type plasminogen activator kringle, inhibits neovascularization in vitro and in vivo
  • 2014.05 | 2014 KSBMB Annual Meeting | 국제학술대회(포스터)
    UP-7 potently suppresses growth and metastasis of breast cancer
  • 2014.05 | 2014 KSBMB Annual Meeting | 국제학술대회(포스터)
    Peroxidasin is required for proper extracellular assembly of Col IV and FN in endothelial cells
  • 2014.04 | The 18th International Vascular Biology Meeting | 국제학술대회(포스터)
    UP-7 peptide derived from urokinase kringle domain potently inhibits angiogenesis and tumor growth
  • 2014.04 | The 18th International Vascular Biology Meeting | 국제학술대회(포스터)
    Assembly of extracellular matrix by peroxidasin is critical for angiogenic process
  • 2014.04 | 105th AACR Annual Meeting | 국제학술대회(포스터)
    Urokinase kringle-derived peptide UP-7 potently inhibits angiogenesis and tumor growth
  • 2013.12 | The 18 th Annual Meeting of Korean Society of Cancer Prevention | 국제학술대회(구연)
    Peroxidasin, a Unique Enzyme-matrix Protein, is a Putative Novel Target for Anti-angiogenesis
  • 2013.10 | 2013 Annual Meeting of KSAP | 국내학술대회(포스터)
    Peroxidase activity and ECM domain are required for peroxidasin function in endothelial cells
  • 2013.10 | 2013 Annual Meeting of KSAP | 국내학술대회(포스터)
    UP-7 peptide originated from urokinase kringle domain has the anti-angiogenic and anti-tumor activities
  • 2013.08 | The 11th Japan-Korea Joint Symposium on Vascular Biology | 국제학술대회(포스터)
    ECM motifs and peroxidase activity are essential for peroxidasin function in endothelial cells
  • 2013.08 | The 11th Japan-Korea Joint Symposium on Vascular Biology | 국제학술대회(포스터)
    Urokinase kringle-derived peptide UP-7 potently inhibits angiogenesis and tumor growth
  • 2013.07 | 38th FEBS Congress | 국제학술대회(포스터)
    Acceleration of tumor growth by nitric oxide production in macrophages after radiotherapy
  • 2013.07 | 38th FEBS Congress | 국제학술대회(포스터)
    Proangiogenic eatures of umbilical cord matrix-derived mesenchymal stromal/stem cells and their ability to function as perivascular-like cells
  • 2013.05 | 2013 KSBMB Annual Meeting | 국제학술대회(포스터)
    UP-7 peptide derived from urokinase kringle domain potently inhibit angiogenesis and tumor growth
  • 2013.05 | 2013 KSBMB Annual Meeting | 국제학술대회(포스터)
    ROCK inhibitor blocks inhibition of neurite-like structure formation of mesenchymal stem/stromal cells by chondroitin sulfate proteoglycan
  • 2013.05 | 2013 KSBMB Annual Meeting | 국제학술대회(포스터)
    Proangiogenic features of Wharton’s jelly-derived mesenchymal stromal/stem cells and their ability to form vascular networks
  • 2013.05 | 2013 KSBMB Annual Meeting | 국제학술대회(포스터)
    Peroxidase activity is required for Peroxidasin function
  • 2012.12 | The 20th Annual Meeting of the Japanese Vascular Biology and Medicine Organization/ The 10th Korea-Japan Joint Symposium on Vascular Biology | 국제학술대회(구연)
    Non-adhesive culture of cord blood-derived CD34+ fraction for expansion of early endothelial progenitor cells
  • 2012.10 | 2012 Annual Meeting of The Korean Society of Applied Pharmacology | 국제학술대회(포스터)
    Peroxidasin, a cell adhesion protein with peroxidase domain, is a putative novel anti-angiogenic target
  • 2012.10 | 2012 Annual meeting of KSAP | 국제학술대회(포스터)
    Proangiogenic features of Wharton’s jelly-derived mesenchymal stromal/stem cell and thir ability to form functional vessels
  • 2012.08 | 한국혈관연구회 심포지움 | 국내학술대회(구연)
    Peroxidasin is involved in extracellular matrix remodeling and implicated in varicose vein
  • 2012.07 | The 3rd workshop for experimental methods of translational research in gynecologic oncology | 국내학술대회(구연)
    Peroxidasin is a putative novel anti-angiogenic target
  • 2012.06 | 2012 KSBMB Annual Meeting | 국제학술대회(포스터)
    Analysis of expression level of vascular cell markers in Wharton’s jelly derived mesenchymal stromal cells and their ability to form functional vessels
  • 2012.04 | 2012 International Congress of Korean Federation of Pharmaceutical Societies | 국제학술대회(포스터)
    Priming of Wharton’s jelly-derived mesenchymal stromal cells with ROCK inhibitor improves functional recovery of mice with intracerebral hemorrhage stroke
  • 2012.04 | AACR annual meeting | 국제학술대회(포스터)
    Tumor growth inhigitory effect in EIF4B silenced in vitro and in vivo lung cancer models.
  • 2011.11 | 2011 Annual Meeting of KSAP | 국제학술대회(포스터)
    Enhancement of endothelial progenitor cell number and migration by H1152, a Rho kinase specific inhibitor
  • 2011.11 | 2011 Annual Meeting of KSAP | 국제학술대회(포스터)
    Evalution of UK1 and TK1-2-derived peptides for anti-angiogenic and anti-tumor activities
  • 2011.10 | The Second Pacific Symposium on Vascular Biology | 국제학술대회(포스터)
    Peroxidasin, a cell adhesion protein with peroxidase domain, plays a pivotal role in angiogenic endothelial cell functions
  • 2011.10 | The 23rd Annual Meeting of KSMCB | 국제학술대회(포스터)
    Effects of UK1 and TK1-2-drived peptides on angiogenesis and tumor growth in NCI-H640 lung cancer cell xenografted mice
  • 2011.10 | The 23rd Annual Meeting of KSMCB | 국제학술대회(포스터)
    Peroxidasin expression is increased in varicose vein
  • 2011.10 | The 23rd annual meeting of KSMCB | 국제학술대회(포스터)
    Peroxidasin, a cell adhesion protein with peroxidase domain, plays a pivotal role in multiple endothelial cell functions
  • 2011.08 | The 9th Japan-Korea Joint Symposium on Vascular Biology | 국제학술대회(포스터)
    Efficient non-adhesive ex vivo expansion of early endothelial progenitor cells derived from CD34+ human cord blood fraction for effective therapeutic vascularization
  • 2011.06 | 9th Annual Meeting of ISSCR | 국제학술대회(포스터)
    Neuronal induction of Wharton’s jelly-derived mesenchymal stromal cells using rock inhibitor improves therapeutic effect in intracerebral hemorrhage stroke model
  • 2011.05 | 8th Meeting of Asian Society for Neuro-Oncology | 국제학술대회(구연)
    Anti-angiogennicity accompained by down-regulated O6-methylguanine-DNA METHYLTRANFERASE EXPRESSION IN ENDOTHELIAL CELLS
  • 2011.05 | 2011 KSBMB Annual Meeting | 국제학술대회(포스터)
    Fasudil promotes neuronal differentiation of Wharton’s jelly-derived mesenchymal stromal cells and their therapeutic effect in intracerebral hemorrhage stroke model
  • 2010.11 | 2010 Annual Meeting of KSAP | 국제학술대회(포스터)
    Fasudil augments endothelial cell number and neovascularization in a hindlimb ischemia
  • 2010.11 | 2010 Annual Meeting of KSAP | 국제학술대회(포스터)
    The effects of Rho kinase inhibitors on neuronal differentiation of mesenchymal stromal cells derived from human bone marrow
  • 2010.10 | The 22nd Annual Meeting of KSMCB | 국제학술대회(포스터)
    Non-adhesive ex vivo expansion of early endothelial progenitor cells derived from CD34+ human cord blood fraction for effective therapeutic vascularization
  • 2010.10 | The 22nd Annual Meeting of KSMCB | 국제학술대회(포스터)
    A comparison of ROCK inhibitors on human bone marrow-derived mesenchymal stem cell differentiaiton into neuron-like cells
  • 2010.10 | The 22nd Annual Meeting of KSMCB | 국제학술대회(포스터)
    Wharton's jelly-derived mesenchymal stromal cells promote neovascularization and perfusion in a murine hindlimb ischemia model
  • 2010.05 | 2010 KSBMB Annual Meeting | 국제학술대회(포스터)
    The effect of mesenchymal stromal cells derived from Wharton's jelly on therapeutic neovascularization
  • 2010.05 | 2010 KSBMB Annual Meeting | 국제학술대회(포스터)
    ROCK inhibition promotes the differentiation of Wharton's jelly-derived mesenchymal stromal cells into neuron-like cells
  • 2010.05 | 2010 KSBMB Annual Meeting | 국제학술대회(포스터)
    Efficient non-adhesive ex vivo expansion of early endothelial progenitor cells from human cord blood CD34+ fraction
  • 2010.05 | 2010 KSBMB Annual Meeting | 국제학술대회(포스터)
    Fasudil, a Rho kinase inhibitor, enhances the number and functions of endothelial progenitor cells
  • 2009.12 | 49th Annual Meeting of the American Society for Cell Biology | 국제학술대회(포스터)
    DGDA, a local sequnce of the kringle 2 domain, is a functional motif of the antiangiogenic kringle domain of tissue-type plasminogen activator
  • 2009.11 | 2009 Annual Meeting of The Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    The effects of Rho kinase inhibitors in endothelial progenitor cells
  • 2009.11 | 2009 Annual Meeting of The Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    DGDA sequence derived from TK1-2 provides a potential novel antiantiogenic peptide
  • 2009.11 | 2009 Annual Meeting of The Korean Society of Applied Pharmacology | 국내학술대회(포스터)
    Charaterization and neuronal differentiation of mesenchymal stromal cells derived from Wharton's jelly
  • 2009.04 | 100th Annual Meeting 2009 | 국제학술대회(포스터)
    Enhancement of anti-tumor activity by low-dose combination of the recombinant urokinase kringle domain and celecoxib in a malignant glioma xenograft model.
  • 2008.10 | 13th Workd congress on advances in oncology and 11th International symposium on molecuar medicine | 국제학술대회(구연)
    Anti-angiogenic effect of TK1-2 is in part attributalbe to inhibition of integrin a2b1
  • 2008.10 | The 9th International Congress on Cell Biology & The 20th annual conference of the KSMCB | 국제학술대회(포스터)
    Characterization of mesenchymal stromal cells derived from Wharton's Jelly and effects of Rho-kinase inhibitor on their neuronal differentiation
  • 2008.10 | The 20th annual conference of the KSMCB | 국제학술대회(포스터)
    Fasudil enhances adhesive differentiation of endothelial progenitor cells
  • 2008.09 | 제94차 대한산부인과학회 학술대회 | 국내학술대회(구연)
    Human placental membrane : a extensive source for mesenchymal stem cells with differentiation into osteocyte, chondrocyte, and adipocyte in vitro
  • 2008.08 | 제 26회 세포생물학회 | 국내학술대회(구연)
    TK1-2 inhibits endothelial progenitor cell differentiation and its contribution to tumor angiogenesis in vivo
  • 2008.06 | The 34th annual meeting of Korean Cancer Association | 국제학술대회(포스터)
    Anti-angiogenic effect of TK1-2 is mediated through the disruption of signaling pathway by interfering with integrin a2b1
  • 2008.05 | The 65th KSBMB annual meeting | 국제학술대회(포스터)
    Kringle domain of tissue-type plasminogen activator inhibits extracellular matrix-induced adhesion and migration of endothelial cells
  • 2008.05 | The 65th KSBMB annual meeting | 국제학술대회(포스터)
    Anti-migration effect of TK1-2 is mediated in part by interfering with integrin a2b1
  • 2008.05 | The 65th KSBMB annual meeting | 국제학술대회(포스터)
    Integrin avb3 is not significantly implicated in the anti-migratory effect of anti-angiogenic urokinse kringle domain
  • 2008.05 | The 65th KSBMB annual meeting | 국제학술대회(포스터)
    Comparison of cytokines for ex vivo expansion of endothelial progenitor cells derived from human umbilical cord blood by suspension culture
  • 2008.02 | 분자암연구학회 | 국내학술대회(구연)
    TK1-2 inhibits endothelial function and its contribution to tumor angiogenesis
  • 2007.08 | Japan-Korea Joint Symposium on Vascular Biology, 2007 | 국제학술대회(구연)
    TK1-2, an angiogenesis inhibitor, effectively inhibits tumor angiogenesis by ex vivo differentiated endothelial progenitor cells
  • 2007.07 | 32nd FEBS Congress | 국제학술대회(포스터)
    Delayed senescence of outgrowing endothelial progenitor-derived cells provides an efficient vasculogenesis tool
  • 2007.06 | 제 33차 대한 암학회 정기 학술대회 | 국내학술대회(포스터)
    Tumor angiogenesis promoted by ev vivo differentiated endothelial progenitor cells is effectively inhibited by an angiogenesis inhibitor, TK1-2
  • 2006.12 | IVth Korea-Japan Joint Symposium on Vascular Biology. | 국제학술대회(포스터)
    Outgrowing endothelial progenitor-derived cells display high sensitivity to angiogenesis modulators and delayed senescence.
  • 2006.12 | IVth Korea-Japan Joint Symposium on Vascular Biology. | 국제학술대회(포스터)
    TK1-2 inhibits endothelial cell migration by perturbing migration signaling pathway and cytoskeleton rearrangement via interaction with integrin α2β1.
  • 2006.10 | The 18th annual meeting of the Korean society for molecular and cellular biology | 국제학술대회(포스터)
    Interaction with integrin α2β1 involved in the inhibitory effect of TK1-2 on endothelial cell migration.
  • 2006.10 | The 18th annual meeting of the Korean society for molecular and cellular biology | 국제학술대회(포스터)
    Outgrowing endothelial progenitor-derived cells display high sensitivity to angiogenesis inhibitors and delayed senescence.
  • 2006.07 | Korea Conference on Innovative Science and Technology 2006-Vascular Biology and Human Disease | 국제학술대회(포스터)
    TK1-2 inhibits endothelial cell migration through the disruption of cytoskeleton rearrangement via interaction with integrin a2b1
  • 2006.06 | The 31st FEBS Congress | 국제학술대회(포스터)
    The kringle domain of T-PA inhibits endothelial cell migration by perturbing FAK and ERK1/2 activation.
  • 2006.06 | The 32nd annual meeting of Korean cancer association | 국제학술대회(포스터)
    The recombinant kringle domain of tissue-type plasminogen activator inhibits in vitro and in vivo functions of endothelial progenitor cells.
  • 2006.06 | The 32nd annual meeting of Korean cancer association | 국제학술대회(포스터)
    Characterization of outgrowing endothelial progenitor cells as an effective tool for angiogenesis assay.
  • 2005.10 | Stem cells, Senescence and Cancer | 국제학술대회(포스터)
    Differential contribution of ex vivo-cultivated endothelial progenitor cells and HUVECs to tumor vascularization in A549 xenografted mice
  • 2005.10 | 2005 한국분자-세포생물학회 추계학술대회 | 국내학술대회(포스터)
    Expression and characterization of non-glycosylated TK1-2 and its anti-angiogenic activity
  • 2005.08 | 15th KSMCR 2005 Summer Conference | 국내학술대회(구연)
    The inhibitory effects of an antiangiogenic molecule, TK1-2, on endothelial progenitor cell differentiation and their incorporation into tumor vasculature
  • 2005.08 | Japan-Korea Joint Symposium on Vascular Biology | 국제학술대회(포스터)
    Effect of TK1-2 on contribution of endothelial progenitor cells to tumor vascularization
  • 2005.07 | 2005 상록 심포지움 | 국내학술대회(구연)
    The inhibitor mechanism of an antiangiogenic molecule, TK1-2, in endothelial cell migration and its effect on endothelial progenitor cells
  • 2005.06 | The 31th Annual meeting of Korea Cancer Association | 국내학술대회(포스터)
    Suppression of vivo maiignant glioma growth by the kringle domain of urokinase plasminogen activator and its combination effect
  • 2005.06 | The 31th Annual Meeting of Korean Cancer Association | 국내학술대회(포스터)
    Combined Effect of Temozolomide and Interferon-B in Gliomas
  • 2005.05 | 62nd KSBMB meeting in 2005 | 국내학술대회(포스터)
    Selective inhibition of endothelial cell migration by TK1-2 through ERK1/2 inhibition followed by intracellular localization
  • 2005.03 | 2005 Experimetal Biology | 국제학술대회(포스터)
    The kringle domain of tissue-type plasminogen activator inhibits differentiation and migration of endothelial progenitor cells
  • 2004.12 | 44nd American Society for Cell Biology Annual Meeting | 국제학술대회(포스터)
    TK1-2 Disturbs Activation of Extracellular Signal-regulated Kinase 1/2 and Cytoskeletal Reorganization
  • 2004.11 | The 1st Annual Meeting of the Japanese Vascular Biology and Medicine Organization & Korea-Japan Joint Symposium on Vascular Biology 2004 | 국제학술대회(구연)
    Targeting Endothelial Progenitor Cell Differentiation for Angiogenesis Inhibition: a Possible Role of Angiogenesis Inhibitors
  • 2004.11 | The 1st Annual Meeting of the Japanese Vascular Biology and Medicine Organization & Korea-Japan Joint Symposium on Vascular Biology 2004 | 국제학술대회(포스터)
    Anti-tumor activity of TK1-2 and its cellular mechanism of anti-angiogenesis
  • 2004.11 | The 1st Annual Meeting of the Japanese Vascular Biology and Medicine Organization & Korea-Japan Joint Symposium on Vascular Biology 2004 | 국제학술대회(포스터)
    RGD-dependent cell adhesion is pivotal for in vitro endothelial progenitor cell differentiation
  • 2004.10 | 2004 대한생화학, 분자생물학회 추계국제학술대회 | 국내학술대회(포스터)
    Inhibitory effects of RGD peptide on endothelial progenitor cell differentiation
  • 2004.10 | 2004 대한생화학, 분자생물학회 추계국제학술대회 | 국내학술대회(포스터)
    TK1-2 Disturbs Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) and Cytoskeletal Reorganization
  • 2004.10 | 2004 대한생화학, 분자생물학회 추계국제학술대회 | 국내학술대회(포스터)
    Effect of nimesulide on the differentiation and survival of endothelial progenitor cells
  • 2004.09 | 제 14차 한국혈전지혈학회 학술대회 | 국내학술대회(포스터)
    Anti-angiogenic Activity of the Recombinant Kringle Domain of Urokinase (UK1) and Effect of the UK1 on Proteolytic Activity of uPA
  • 2004.07 | 제3회 기초-임상 연구위원회 합동 세미나 | 국내학술대회(구연)
    Regulation of endothelial progenitor cell differentiation
  • 2004.06 | 제 30차 대한암학회 학술대회 | 국내학술대회(포스터)
    The effect of TK1-2 on endothelial cell migration, an important process in angiogenesis
  • 2004.06 | 제 30차 대한암학회 학술대회 | 국내학술대회(포스터)
    Inhibition of endothelial progenitor cell differentiation by TK1-2
  • 2003.12 | 2nd Meeting of the Asian Society for Neuro-oncolog | 국제학술대회(구연)
    TK1-2, Two-kringle domain of tissue-type plasminogen activator, is a novel anti-angiogenic agent
  • 2003.11 | The Korean Federation of Science and Technology So | 국제학술대회(구연)
    Anti-angiogenic activities of the kringle domains of plasminogen activators
  • 2003.08 | 제 11회 분자암연구회 여름모임 | 국내학술대회(포스터)
    Inhibition of primary tumor growth in vivo by the recombinant kringle domain of tissue-type plasminogen activator
  • 2003.08 | 제 11회 분자암연구회 여름모임 | 국내학술대회(구연)
    Inhibition of angiogenesis and tumor growth by plasminogen activator kringles
  • 2003.08 | Korea-Japan joint symposium on vascular biology | 국내학술대회(포스터)
    Inhibitory effects of Myoseverin, a microtubule-binding molecule, on differentiation of engothelial progenitor and mature endothelial cells
  • 2003.07 | 94th Annual Meeting of AACR | 국제학술대회(구연)
    Inhibition of human lung tumor growth in vivo by the recombinant kringle domain of tissue-plasminogen activator
  • 2003.06 | 제 29차 대한암학회 | 국내학술대회(포스터)
    Identification of the recombinant kringle domain of t-PA as a novel anti-angiogenic agent
  • 2003.06 | 제 29차 대한암학회 | 국내학술대회(포스터)
    Inhibitory effects of tubulyzines on endothelial progenitor cell differentiation
  • 2003.06 | 제 29차 대한암학회 | 국내학술대회(포스터)
    The recombinant kringle domain of tissue-type plasminogen activator suppresses primary tumor growth
  • 2003.06 | 소화기내과 집담회 | 국내학술대회(구연)
    Tumor angiogenesis: a target for overcoming drug resistance
  • 2003.04 | 2003 한국응용약물학회 춘계학술대회 | 국내학술대회(구연)
    재조합 크링글 도메인 UK-1과 TK1-2의 혈관 신생 억제작용과 항암효과
  • 2003.03 | 제3회 암전이 연구기법 연수강좌 | 국내학술대회(구연)
    EPC isolation and culture
  • 2002.12 | 42nd The American Society for Cell Biology Annual | 국내학술대회(구연)
    Anti-angiogenic activity of the recombinant kringle domain of urokinase and its endothelial-cell specific internalization
  • 2002.10 | 제14회 한국분자·세포생물학회 추계학술대회 | 국내학술대회(포스터)
    High-Level Secretion of the Recombinant Urokinase Kringle Domain in Pichia pastoris
  • 2002.10 | 대한신경외과학회 제42차 추계학술대회 | 국제학술대회(포스터)
    Inhibition of metastasis, angiogenesis, and growth of 9L gliosarcoma in vivo by a recombinant apolipoprotein(α) kringle, LK8
  • 2002.10 | 제14회 한국분자·세포생물학회 추계학술대회 | 국내학술대회(포스터)
    The Effects of Microtubule-binding molecules on differentiation of cord blood-derived endothelial precursor cells
  • 2002.09 | 가톨릭암센터 임상증례,암연구 발표 | 국제학술대회(포스터)
    Anti-tumor activity of angiogenesis inhibitor and its cellular mechanism of action
  • 2002.07 | 제9회 2002년 대한분자암연구학회 여름모임 | 국제학술대회(포스터)
    Anti-angiogenic activity of the kringle domain of urokinase and its cellular mechanism of action
  • 2002.06 | 제28차 대한암학회 학술대회 | 국제학술대회(포스터)
    Anti-endothelial Cell Activities of the Recombinant Kringle Domain of Urokinase and its EndothelialCell Specific Entry
  • 2002.06 | 대한뇌종양학회 제12차 정기학술대회 | 국제학술대회(포스터)
    Inhibition of growth, Angiogenesis, and Metastasis of 9L Gliosarcoma In Nude Mice By A Apolipoprotein(A) Kringle, LK8
  • 2002.05 | 대한건선학회 제6차 학술대회 | 국제학술대회(포스터)
    Selective Culture of Endothelial Progenitor Cells from Human Umbilical Cord Blood
  • 2002.03 | 영동생명과학연구회 분자생물학 심포지움 | 국제학술대회(포스터)
    Anti-angiogenic activity of urokinase kringle domain and in vitro differntiation of endothelial precursor cells
  • 2001.11 | 강원대학교 생명과학 심포지움 | 국제학술대회(포스터)
    Interaction of the serine protease urokinase-type plasminogen activator (uPA) kringle with the endothelial cells
  • 2001.11 | 강원대학교 생명과학 심포지움 | 국제학술대회(포스터)
    In vitro differentiation of endothelial precursor cells
  • 2001.10 | 2001년도 한국생화학회 추계학술대회 |
    Interaction of the serine protease urokinase-type plasminogen activator (uPA) kringle with the endothelial cells
  • 2001.10 | 2001년 한국생화학회 추계학술대회 | 국내학술대회(포스터)
    Characterization of a potent angiogenesis inhibitor recombinant apolipoprotein(a) kringles 36-38 (rLK68) in vivo and in vitro
  • 2001.10 | 6th World Congress of Advances in Oncology and 4th | 국제학술대회(구연)
    Angiogenesis inhibition for the treatment of brain tumor: Kringles 1-3 and interferon-b
  • 2001.10 | International convention of the pharmaceutical soc | 국제학술대회(구연)
    Anti-angiogenic Activity of the Recombinant Kringle Domain of Human Urokinase
  • 2001.10 | 제45차 대한순환기학회 추계학술대회 | 국제학술대회(포스터)
    Endothelial Progenitor Cell의 체외 증폭과 분화에 관한 연구
  • 2001.05 | 14th International Conference on Brain Tumor Resea | 국내학술대회(구연)
    Efficient inhibition of in vivo malignant glioma growth and angiogenesis by interferon-β treatment at early stage of tumor development
  • 2001.05 | 14th International Conference on Brain Tumor Resea | 국내학술대회(구연)
    Vascular endothelial growth factor (VEGF) induction inhibits apoptotic cell death caused by irradiation in human malignant glioma cells
  • 2001.04 | 2001년도 대한신경외과학회 제19차 춘계학술대회 | 국내학술대회(포스터)
    Efficient inhibition of in vivo malignant glioma growth and angiogenesis by interferon-β treatment at early stage of tumor development
  • 2000.12 | 40th Annual Meeting of ASCB | 국내학술대회(구연)
    Effect of N¹-guany-1, 70diaminoheptane, an inhibitor of deoxyhypusine synthase, on endotheial cell growth, differentiation and apoptosis
  • 2000.11 | 대한순환기학회 추계 학술대회 | 국내학술대회(포스터)
    Endothelial Progenitor Cell의 체외증폭과 Vasculogenesis에 미치는 영향
  • 2000.08 | 제2회 안지오제네시스 심포지움 | 국제학술대회(포스터)
    Angiostatic activites of recombinant kringle and amino-terminal fragment of u-PA
  • 2000.07 | International Congress of Fibrinolysis & Proteolys |
    Antiangiogenic activity of recombinant kringle and amino-terminal fragment of urokinase-type plasminogen activator
  • 2000.04 | 2000년 대한신경외과학회 제18차 춘계학술대회 | 국제학술대회(포스터)
    Enhanced Antitumor Effect by combination of p53 Gene Transfer and Irradiation in Human Glioma CellsExpressing Mutant and Wild Type p53
  • 2000.04 | 2000 Annual Meeting of American Association of Neu | 국내학술대회(구연)
    Suppression of Angiogenesis and Malignant Glioma Growth by Recombinant Angiostatin
  • 1999.10 | 6th IUBMB Seoul Conference | 국내학술대회(구연)
    Disruption of interkringle disulfide bond of plasminogen kringle 1-3 changes lysine binding capability of kringle 2, but not its antiangiogenic activity
  • 1999.06 | 제25회 대한암학회 학술대회 | 국내학술대회(포스터)
    Inhibition of human malignant glioma growth in vivo by human recombinant plasminogen kringles 1-3
  • 1999.05 | ASBMB annual meeting | 국내학술대회(구연)
    Complex formation between deoxyhypusine synthase and its protein
  • 1999.05 | 제3차 가톨릭대학교 의과학 연구원 학술대회 | 국제학술대회(포스터)
    Structural features of endostatin required for angiogenesis inhibition
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